ASCIMINIB 40 mg (Kyzific) x 60 Tablets

Uses of ASCIMINIB 40 mg

• Treats chronic myeloid leukemia (CML) in adults.
• Used in Philadelphia chromosome-positive CML.
• Used in patients who are resistant or intolerant to other TKIs (like imatinib, dasatinib, nilotinib).
• Helps control disease in advanced or chronic phases.

Benefits of ASCIMINIB 40 mg

• Targets cancer cells more precisely than older TKIs.
• Works in cases where other treatments fail.
• Helps reduce leukemia cell levels.
• Oral therapy with convenient dosing.
• May improve long-term disease control.

How does it work?

Asciminib is a targeted cancer medicine that works as a STAMP inhibitor (Specifically Targeting the ABL Myristoyl Pocket). It blocks the BCR-ABL1 protein that drives chronic myeloid leukemia, stopping the abnormal signaling that causes uncontrolled white blood cell growth.

Precautions

• Take exactly as prescribed.
• Do not change dose without doctor advice.
• Take on an empty stomach or as directed.
• Monitor blood counts regularly.
• Inform your doctor about heart, liver, or pancreas problems.
• Tell your doctor about all medicines you are taking.
• Report severe fatigue, abdominal pain, or unusual symptoms immediately.

Side Effects

• Fatigue
• Nausea
• Headache
• Low blood cell counts