XPREZA (Azacitidine 300 mg) x 14 Tablets

Uses of Azacitidine 300 mg

• Treats myelodysplastic syndromes (MDS).
• Used in acute myeloid leukemia (AML), especially in older or unfit patients.
• Helps control abnormal bone marrow cell growth.
• Used in certain blood cancers under specialist supervision.

Benefits of Azacitidine 300 mg

• Improves bone marrow function and blood counts.
• Slows progression of MDS and AML.
• Reduces need for blood transfusions.
• May improve survival in high-risk patients.
• Useful when intensive chemotherapy is not suitable.

How does it work?

Azacitidine is a hypomethylating agent. It works by blocking abnormal DNA methylation in bone marrow cells, which helps reactivate normal gene expression. This slows the growth of cancerous blood cells and improves production of healthy blood cells.

Precautions

• Given only as injection under medical supervision.
• Regular blood count monitoring is required.
• Inform your doctor about liver or kidney problems.
• Watch for signs of infection, fever, or bleeding.
• Tell your doctor about all medicines you are taking.
• Avoid pregnancy during treatment.
• Report severe weakness, persistent fever, or unusual bruising immediately.

Side Effects

• Fatigue
• Nausea or vomiting
• Low blood cell counts
• Fever or infections
• Loss of appetite

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