Nublexa (REGORAFENIB 40 mg) x 28 Tablets

Uses of REGORAFENIB 40 mg

• Treats metastatic colorectal cancer (CRC).
• Used for gastrointestinal stromal tumors (GIST) after prior treatments.
• Treats advanced hepatocellular carcinoma (HCC).
• Helps slow the progression of advanced cancers.
• Used when certain other cancer treatments are no longer effective.

Benefits of REGORAFENIB 40 mg

• Specifically targets cancer cell growth.
• Blocks the formation of blood vessels that nourish tumors.
• Helps slow the growth and spread of cancer.
• May improve progression-free and overall survival.
• Supports long-term disease control.
• Convenient oral tablet taken once daily.
• May help reduce tumor progression.
• Helps maintain quality of life during treatment.
• Offers a targeted treatment option for advanced cancers.
• Can be used after failure of previous therapies.

How Does It Work?

Regorafenib is a multi-kinase inhibitor that blocks several proteins involved in cancer cell growth, tumor progression, and the formation of new blood vessels. By inhibiting these pathways, it slows the growth and spread of cancer cells while reducing the blood supply that tumors need to survive.

Precautions

• Take the medicine exactly as prescribed by your doctor.
• Take it with a low-fat meal at the same time each day.
• Inform your doctor if you have liver disease, heart disease, or high blood pressure.
• Regular blood tests and liver function tests may be required.
• Monitor your blood pressure throughout treatment.
• Report severe bleeding, chest pain, shortness of breath, or severe skin reactions immediately.
• Avoid grapefruit and grapefruit juice during treatment.
• Inform your doctor about all medicines, vitamins, and herbal supplements you are taking.
• Use effective contraception during treatment and avoid breastfeeding.
• Do not stop or change the dose without consulting your healthcare provider.

Side Effects

• Fatigue and weakness
• Nausea, vomiting, or diarrhea
• High blood pressure (hypertension)
• Hand-foot syndrome (redness, pain, or swelling in hands/feet)
• Mouth sores or loss of appetite

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