The combination of Ledipasvir + Sofosbuvir is prescribed for the treatment of chronic hepatitis C virus (HCV) infection.
Ledipasvir + Sofosbuvir is a prescription medication 2 antiviral medicines:
1. Ledipasvir 90mg
2. Sofosbuvir 400mg
The combination functions via reducing the amount of hepatitis C virus in the body. It also removes the virus from the blood gradually.
Ledipasvir 90mg + Sofosbuvir 400mg is generally prescribed for the treatment of chronic hepatitis C virus (HCV) infection.
Take the medicine with food, preferably at the same time daily.
Take medicine every day for either 12 or 24 weeks.
Do not skip medicine doses as it increases the risk of treatment failure. All doses should be taken on time and as directed.
The medicine may result in some side effects such as:
Fatigue
Dizziness
Blurred vision
Doctor advice patients against doing anything that requires concentration (driving a car or operating any machine).
It is common to experience headaches while under the treatment of Ledipasvir + Sofosbuvir. Hence, you must focus on drinking plenty of water. If the headache gets worse or affect your daily life, take a suitable painkiller under the guidance of your doctor. Inform your doctor if it does not go away.
Your doctor may advice you to monitor your liver function and the amount of hepatitis C virus in your body regularly.
Strictly avoid stopping this medicine without your doctor’s advice.
If you are a hepatitis B patient, taking ledipasvir and sofosbuvir as a treatment course may make the virus active or get worse while using or after you stop using. Hence, it is advised that you go for frequent liver function tests for several months after stopping the medicine.
Many times, Ledipasvir and sofosbuvir is prescribed in combination with other medication. Always read the guide that comes with medication or patient instructions provided by the doctor in your combination therapy.
The dosage of medicine should not be changed without your doctor's advice.
Prescription Instructions - It is advised to follow all directions given on your prescription label. Read medication guides or instruction sheets given to you carefully. All medicines should be taken exactly as directed by the doctor. Speak to your doctor or pharmacist if you do not understand any of the given instructions.
How to Take - You may take ledipasvir 90mg and sofosbuvir 400mg with or without food. This medicine should be taken at the same time every day.
Consuming Tablets – Strictly avoid chewing the oral pellets. If you are taking the medicine with food, simply mix the pellets with a non-acidic soft food (porridge, pudding, chocolate syrup, ice cream, mashed potato) at room temperature or below. Swallow the entire mixture without chewing. The mixture should be consumed within 30 minutes after mixing. Strictly avoid saving the mixture for later use.
Dosage Prescription – The combination of Ledipasvir and sofosbuvir doses are based on patient’s weight especially among children and teenagers. The dose may change as the patient gains or loses weight. Do not change your dose or dosing schedule without your doctor's advice.
Care during Treatment - You will be advised to get frequent blood tests for monitoring functioning of liver.
Liver Tests – Patients with hepatitis B should get liver function tests for several months after their last dose have this medication. This is recommended because the medicine has a tendency to make Hepatitis B virus active or worse during the treatment or in the months after you stop.
When to Stop? – It is not advised to stop this medicine suddenly. This may make the condition harder to treat with hepatitis C antiviral medicine.
Doctor’s Guidance – All patients with chronic hepatitis C should remain under the guidance of a doctor.
It is advised to take the medicine as soon as you remember. However, if it is almost time for your next dose, skip it. Strictly avoid taking two doses at one time.
Get your prescription refilled before you run out of medicine completely.
The following listed allergic reactions should be reported to doctor immediately:
Hives
Difficult breathing
Swelling of your face Lips, Tongue, Throat
It is advised to seek emergency medical when you observe any of the following new or worsening symptoms:
Pain in right-sided upper stomach
Vomiting
Loss of appetite
Jaundice (yellowing of the skin or eyes)
Not feeling well
In case, you take ledipasvir and sofosbuvir combined with a heart rhythm medicine (amiodarone), the combination may lead to dangerous side effects on your heart. It is advised to seek medical help right away if you take these medicines and observe the following side effects:
Very slow heartbeats
Pain in chest
Shortness of breath
Confusion
Issues related to memory
Weakness, extreme tiredness, light-headed feeling (feels like you might pass out).
Common side effects of this medicine may include:
Weakness
Headache
Feeling tired
Additional InformationThese medicines should be strictly kept out of reach of children.
Strictly avoid sharing medicines with others.
Use of this medicine should be given only as prescribed.
It is advised to always consult your medical professional to ensure the information displayed on this page is applicable to your personal circumstances.